Diabetes is a chronic, progressive disease characterized by elevated blood glucose levels. Diabetes can lead to complications such as cardiovascular disease, damage to eyes, kidneys and nerves, and premature death. Globally, more than 400 million adults live with diabetes, and diabetes directly caused 1....
Farrell, B;
Black, C;
Thompson, W;
McCarthy, L;
Rojas-Fernandez, C;
Lochnan, H;
Shamji, S;
Upshur, R;
Bouchard, M;
Welch, V.
OBJECTIVE: To develop an evidence-based guideline to help clinicians make decisions about when and how to safely taper, stop, or switch antihyperglycemic agents in older adults. METHODS: We focused on the highest level of evidence available and sought input from primary care professionals in guideline de...
Jacobi, J;
Bircher, N;
Krinsley, J;
Agus, M;
Braithwaite, S. S;
Deutschman, C;
Freire, A. X;
Geehan, D;
Kohl, B;
Nasraway, S. A;
Rigby, M;
Sands, K;
Schallom, L;
Taylor, B;
Umpierrez, G;
Mazuski, J;
Schunemann, H.
Objective: To evaluate the literature and identify important aspects of insulin therapy that facilitate safe and effective infusion therapy for a defined glycemic end point. Methods: Where available, the literature was evaluated using Grades of Recommendation, Assessment, Development, and Evaluation (GRA...